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采用二分采样的高分辨率环形正电子断层扫描仪:二分体-I型

High-resolution circular ring positron tomograph with dichotomic sampling: Dichotom-I.

作者信息

Cho Z H, Hilal S K, Ra J B, Hong K S, Bigler R E, Yoshizumi T, Wolf A P, Fowler J S

出版信息

Phys Med Biol. 1983 Nov;28(11):1219-34. doi: 10.1088/0031-9155/28/11/003.

Abstract

The circular ring transaxial positron camera developed earlier was refitted with a new dichotomic sampling scheme and aperture collimators on the detector array to improve the sampling and the overall system resolution. The z-axis slice thickness collimators were also limited to 1 cm, which corresponds to a slice thickness of 0.5 cm FWHM. Two different types of aperture collimators were adopted for high resolution (HR) and very high resolution (VHR) imaging, respectively. In HR mode a resolution of 6.5 mm FWHM was obtained without appreciable degradation of overall sensitivity, which represents a threefold improvement in resolution over the original system. In phantom studies with HR mode a sensitivity of 4500 counts s-1 muCi-1 cm-3 was obtained for a 20 cm diameter uniform phantom filled with water. A VHR mode experiment was also conducted to observe the ultimate resolution capability of the Dichotom-I system, and a resolution of 4.2 mm FWHM was obtained at the expense of sensitivity which was reduced by a factor of four from the HR mode experiment. The experience gained with Dichotom-I suggests a relatively simple and inexpensive modification of the existing NaI(T1) ring positron cameras, most of which suffer from low resolution due to poor sampling and poor intrinsic detector resolution.

摘要

早期开发的环形轴向正电子相机进行了改装,在探测器阵列上采用了新的二分采样方案和孔径准直器,以改善采样和整体系统分辨率。z轴切片厚度准直器也限制为1厘米,这对应于半高宽为0.5厘米的切片厚度。分别采用两种不同类型的孔径准直器用于高分辨率(HR)和超高分辨率(VHR)成像。在HR模式下,获得了半高宽为6.5毫米的分辨率,而整体灵敏度没有明显下降,这比原始系统的分辨率提高了两倍。在使用HR模式的体模研究中,对于直径为20厘米、充满水的均匀体模,获得了4500计数·秒⁻¹·微居里⁻¹·厘米⁻³的灵敏度。还进行了一次VHR模式实验,以观察Dichotom-I系统的极限分辨率能力,获得了半高宽为4.2毫米的分辨率,但灵敏度有所下降,与HR模式实验相比降低了四倍。在Dichotom-I上获得的经验表明,对现有的碘化钠(铊)环形正电子相机进行相对简单且成本低廉的改装是可行的,其中大多数相机由于采样不佳和探测器固有分辨率低而存在分辨率低的问题。

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