Phelps C J, Sladek J R
Brain Res Bull. 1983 Dec;11(6):735-40. doi: 10.1016/0361-9230(83)90016-3.
Catecholamine histofluorescence patterns were examined in brains of young and aged rats, 1 to 14 days following neurosurgical transection of the medial forebrain bundle. At all ages examined, two phenomena were observed: degeneration of nerve fibers and vigorous regrowth of catecholamine-containing fibers in the lesion site. Regenerated catecholamine fibers invaded the area of scarred tissue. This invasion of the scarred area implies that the robust plasticity of catecholaminergic pathways, known to exist in young animals, persists in aged brain.
在内侧前脑束进行神经外科横断术后1至14天，对年轻和老年大鼠的大脑进行了儿茶酚胺组织荧光模式检查。在所有检查的年龄组中，观察到两种现象：神经纤维变性以及损伤部位含儿茶酚胺纤维的旺盛再生。再生的儿茶酚胺纤维侵入了瘢痕组织区域。瘢痕区域的这种侵入意味着已知存在于幼龄动物中的儿茶酚胺能通路的强大可塑性在老年大脑中持续存在。
