Sarokhan A J, Scott R D, Thomas W H, Sledge C B, Ewald F C, Cloos D W
J Bone Joint Surg Am. 1983 Oct;65(8):1071-80.
From 1971 to 1981, total knee arthroplasty was performed on forty-eight knees in twenty-eight patients with juvenile rheumatoid arthritis at the Robert Breck Brigham (now Brigham and Women's) Hospital. Seventeen of these patients, with twenty-nine knee-replacement arthroplasties, were followed for from two to eleven years (average, five years) and are the basis for this study. The patients' ages at operation ranged from thirteen to thirty-nine years (average, twenty-three years). Six patients had undergone total hip arthroplasty prior to admission for total knee replacement, and five patients had a total hip replacement performed while they were hospitalized for the knee arthroplasty. Thirteen patients (twenty-one knees) had significant preoperative pain but only three (five knees) had severe discomfort. Four patients were unable to walk, three were household walkers, and ten were limited community walkers. Preoperative deformities of the knees ranged from 20 degrees of varus angulation to 35 degrees of valgus angulation. The average preoperative flexion deformity was 23 degrees and the arc of motion averaged 45 degrees. At follow-up, twenty of the twenty-one knees that had been significantly painful preoperatively were completely relieved of discomfort. The average arc of motion increased by 34 degrees, while in all but one knee the angular deformity had been corrected to zero to 10 degrees of valgus angulation. All but one patient became a limited or full community walker. Complications included one late deep infection and one posterior tibial subluxation. Four knees required subsequent resurfacing of the patella for treatment of pain. We now routinely resurface the patella in all patients with juvenile rheumatoid arthritis who have a total knee replacement. To date no prosthesis has required revision for loosening. Radiolucency of one millimeter or less about the prosthesis was noted at follow-up in eight (30 per cent) of the knees. As custom-made components were required in twelve of the twenty-nine knees, it is obvious that preoperative planning is crucial in the treatment of these patients. Our recent experience has shown that the use of preoperative and postoperative serial casts aids greatly in the correction of severe flexion deformity of the knee. Postoperative manipulation was required for twenty-one of the twenty-nine knees. Skeletal immaturity was not an absolute contraindication to surgery. We think that our results, which showed a marked improvement in both knee function and in quality of life, make the short and long-term risks of knee-implant surgery well worth taking in this patient population.
1971年至1981年期间,在罗伯特·布雷克·布里格姆医院(现布莱根妇女医院),对28例青少年类风湿性关节炎患者的48个膝关节进行了全膝关节置换术。其中17例患者接受了29次膝关节置换手术,随访时间为2至11年(平均5年),这些患者是本研究的基础。患者手术时的年龄在13岁至39岁之间(平均23岁)。6例患者在接受全膝关节置换术前已接受全髋关节置换术,5例患者在因膝关节置换住院期间接受了全髋关节置换术。13例患者(21个膝关节)术前有明显疼痛,但只有3例(5个膝关节)有严重不适。4例患者无法行走,3例为家庭活动者,10例为社区活动受限者。术前膝关节畸形范围从内翻20度到外翻35度。术前平均屈曲畸形为23度,活动弧度平均为45度。随访时,术前有明显疼痛的21个膝关节中有20个完全缓解了不适。平均活动弧度增加了34度,除1个膝关节外,所有膝关节的角度畸形均已矫正至外翻0度至10度。除1例患者外,所有患者均成为社区活动受限者或完全能够在社区活动。并发症包括1例晚期深部感染和1例胫骨后脱位。4个膝关节因疼痛需要随后进行髌骨表面置换。我们现在对所有接受全膝关节置换的青少年类风湿性关节炎患者常规进行髌骨表面置换。迄今为止,尚无假体因松动而需要翻修。随访时,29个膝关节中有8个(30%)在假体周围出现了1毫米或更小的透亮区。由于29个膝关节中有12个需要定制组件,显然术前规划对这些患者的治疗至关重要。我们最近的经验表明,术前和术后使用连续石膏对矫正膝关节严重屈曲畸形有很大帮助。29个膝关节中有21个需要术后手法治疗。骨骼未成熟并非手术的绝对禁忌证。我们认为,我们的结果显示膝关节功能和生活质量均有显著改善,这使得在该患者群体中进行膝关节置换手术的短期和长期风险是值得承担的。