Read N W, Bartolo D C, Read M G, Hall J, Haynes W G, Johnson A G
Br J Surg. 1983 Nov;70(11):656-9. doi: 10.1002/bjs.1800701105.
Anorectal manometry was carried out at rest, during balloon distension of the rectum and during rectal infusion of saline in 19 patients with haemorrhoids, 30 patients with descending perineum syndrome and 21 controls. Basal and squeeze pressures were significantly higher in patients with haemorrhoids than patients with the descending perineum syndrome. A lower rectal volume was required to inhibit internal sphincter tone in patients with descending perineum syndrome compared with control subjects or patients with haemorrhoids. During rectal infusion of saline basal and peak anal pressures in patients with the descending perineum syndrome were lower than in haemorrhoid patients. Peak rectal pressure was abnormally high in both groups. These differences in anorectal function suggest that despite a similar presentation, the two conditions have a different pathogenesis. Moreover, inappropriate anal sphincter stretch or mucosal excision in patients with descending perineum syndrome may lead to severe incontinence.
对19例痔疮患者、30例会阴下降综合征患者和21名对照者在静息状态、直肠球囊扩张时以及直肠注入生理盐水期间进行了肛门直肠测压。痔疮患者的基础压力和挤压压力显著高于会阴下降综合征患者。与会照者或痔疮患者相比，会阴下降综合征患者抑制内括约肌张力所需的直肠容积更低。在直肠注入生理盐水期间，会阴下降综合征患者的基础肛管压力和峰值肛管压力低于痔疮患者。两组患者的直肠峰值压力均异常升高。肛门直肠功能的这些差异表明，尽管临床表现相似，但这两种疾病的发病机制不同。此外，会阴下降综合征患者不适当的肛门括约肌拉伸或黏膜切除可能导致严重失禁。
