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马心脏天冬氨酸氨基转移酶的一级结构及其与其他同型和异型同工酶的比较。

Primary structure of aspartate aminotransferase from horse heart and comparison with that of other homotopic and heterotopic isoenzymes.

作者信息

Martini F, Angelaccio S, Barra D, Doonan S, Bossa F

出版信息

Comp Biochem Physiol B. 1983;76(3):483-7. doi: 10.1016/0305-0491(83)90280-8.

DOI:10.1016/0305-0491(83)90280-8
PMID:6641173
Abstract

Sulphydryl groups of mitochondrial aspartate aminotransferase from horse heart were titrated with 5,5'-dithiobis (2-nitrobenzoic acid). From analysis of peptic peptides, 378 amino acid residues (94.3% of the total) in the protein were identified. The results of amino acid sequence analysis are compared with those of cytosolic and mitochondrial aspartate aminotransferases from other sources.

摘要

用5,5'-二硫代双(2-硝基苯甲酸)滴定马心肌线粒体天冬氨酸氨基转移酶的巯基。通过对胃蛋白酶消化肽段的分析,鉴定出该蛋白质中378个氨基酸残基(占总数的94.3%)。将氨基酸序列分析结果与其他来源的胞质和线粒体天冬氨酸氨基转移酶的结果进行了比较。

相似文献

1
Primary structure of aspartate aminotransferase from horse heart and comparison with that of other homotopic and heterotopic isoenzymes.马心脏天冬氨酸氨基转移酶的一级结构及其与其他同型和异型同工酶的比较。
Comp Biochem Physiol B. 1983;76(3):483-7. doi: 10.1016/0305-0491(83)90280-8.
2
Partial amino-acid sequence and cysteine reactivities of cytosolic aspartate aminotransferase from horse heart.马心肌细胞溶质天冬氨酸氨基转移酶的部分氨基酸序列及半胱氨酸反应活性
Biochim Biophys Acta. 1984 Aug 28;789(1):51-6. doi: 10.1016/0167-4838(84)90059-1.
3
The complete amino acid sequences of cytosolic and mitochondrial aspartate aminotransferases from horse heart, and inferences on evolution of the isoenzymes.马心肌细胞溶质和线粒体天冬氨酸氨基转移酶的完整氨基酸序列及同工酶进化推断
J Mol Evol. 1986;23(4):328-35. doi: 10.1007/BF02100642.
4
Primary structure of aspartate aminotransferase isoenzymes from mammalian heart.
Prog Clin Biol Res. 1984;144B:285-91.
5
Reactivity of sulphydryl groups of cytosolic and mitochondrial bovine aspartate aminotransferases.牛胞质和线粒体天冬氨酸氨基转移酶巯基的反应活性
Mol Cell Biochem. 1981 Mar 13;35(2):121-8. doi: 10.1007/BF02354826.
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The structure of mitochondrial asparate aminotransferase from pig heart and comparison with that of the cytoplasmic isozyme.猪心肌线粒体天冬氨酸氨基转移酶的结构及其与胞质同工酶结构的比较。
FEBS Lett. 1977 Nov 15;83(2):241-4. doi: 10.1016/0014-5793(77)81013-2.
7
The primary structure of mitochondrial aspartate aminotransferase from pig heart: peptides obtained by cleavage with pepsin and with Staphylococcus aureus protease.
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The primary structure of mitochondrial aspartate aminotransferase from pig heart: peptides obtained by cleavage at basic residues.
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The primary structure of mitochondrial aspartate aminotransferase from pig heart: peptides obtained by cleavage with thermolysin and chymotrypsin.
Ital J Biochem. 1979 Nov-Dec;28(6):456-77.
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Syncatalytic conformational changes in mitochondrial aspartate aminotransferases. Evidence from modification and demodification of Cys 166 in the enzyme from chicken and pig.线粒体天冬氨酸氨基转移酶的同步催化构象变化。来自鸡和猪的该酶中半胱氨酸166修饰和解修饰的证据。
J Biol Chem. 1978 May 10;253(9):3158-63.

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2
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3
The complete amino acid sequences of cytosolic and mitochondrial aspartate aminotransferases from horse heart, and inferences on evolution of the isoenzymes.
马心肌细胞溶质和线粒体天冬氨酸氨基转移酶的完整氨基酸序列及同工酶进化推断
J Mol Evol. 1986;23(4):328-35. doi: 10.1007/BF02100642.