Sideris D A, Nanas J N, Chrysos D N, Moulopoulos S D
Eur Heart J. 1983 Aug;4(8):536-46. doi: 10.1093/oxfordjournals.eurheartj.a061519.
An intra-aortic compression chamber system (CCS) was utilized in 19 anaesthetized dogs and in seven patients. The CCS consisted of an intra-aortic balloon in the thoracic aorta, an external rigid wall air chamber, and a catheter connecting the other two parts. The CCS, inflated for 2-3 min to a pressure between the systolic and diastolic arterial pressures, caused changes in the following measurements (compared with those immediately before inflation, and after deflation to atmospheric pressure): a significant (P less than 0.001) increase in cardiac output (7.8 +/- 18.8% means S.D.), aortic compliance (12.8 +/- 29.6%), aortic resistance (20.1 +/- 32.7%), cardiac power (or minute work, + 36.7 +/- 44.6%), coronary sinus outflow (+ 23.6 +/- 43.6%) and aortic backflow (+ 28.0 +/- 36.4%); the left ventricular end-diastolic pressure did not change significantly. During a 5-90 min utilization in seven patients with cardiogenic shock, the cardiac output was increased by 4.1 +/- 42.4% (lower than when intra-aortic balloon pumping was applied). It is concluded that the simple device described may be useful in clinical cardiogenic shock, especially when an intra-aortic balloon pump is not available or a portable device is desirable.
在19只麻醉犬和7例患者中使用了主动脉内压迫腔系统(CCS)。CCS由置于胸主动脉内的主动脉内球囊、外部刚性壁空气腔以及连接其他两部分的导管组成。将CCS充气2 - 3分钟至动脉收缩压和舒张压之间的压力,导致以下测量值发生变化(与充气前及放气至大气压后相比):心输出量显著增加(P小于0.001,均值±标准差为7.8%±18.8%)、主动脉顺应性增加(12.8%±29.6%)、主动脉阻力增加(20.1%±32.7%)、心脏功率(或每分功)增加(+36.7%±44.6%)、冠状窦血流量增加(+23.6%±43.6%)以及主动脉反流增加(+28.0%±36.4%);左心室舒张末期压力无显著变化。在7例心源性休克患者中使用5 - 90分钟期间,心输出量增加了4.1%±42.4%(低于应用主动脉内球囊泵时)。得出的结论是,所描述的这种简单装置可能对临床心源性休克有用,尤其是在没有主动脉内球囊泵可用或需要便携式装置的情况下。