Kardami E, Fiszman M Y
FEBS Lett. 1983 Nov 14;163(2):250-6. doi: 10.1016/0014-5793(83)80829-1.
Tropomyosins can be classified as belonging to an alpha-like or a beta-like family depending on the absence or presence, respectively in their protease-V8 digestion pattern of two peptides with an apparent molecular mass of 21 kDa. Chicken cardiac tropomyosin and the 43 kDa component from gizzard tropomyosin are accordingly classified as alpha-like tropomyosins, while the 33 kDa gizzard tropomyosin component is a beta-like tropomyosin. The 21 kDa peptides have an overall charge which is more positive than that of the intact tropomyosin or any other tropomyosin peptide and probably contain the -NH2 half of the molecule.
原肌球蛋白可根据其蛋白酶-V8消化模式中是否分别存在两条表观分子量为21 kDa的肽段，分为α样或β样家族。因此，鸡心肌原肌球蛋白和来自砂囊原肌球蛋白的43 kDa组分被归类为α样原肌球蛋白，而33 kDa砂囊原肌球蛋白组分是β样原肌球蛋白。21 kDa的肽段整体电荷比完整的原肌球蛋白或任何其他原肌球蛋白肽段更显正性，可能包含分子的-NH2端一半。
