Iino Y, Kobayashi T, Kawamoto K
Jpn J Antibiot. 1983 Sep;36(9):2497-501.
Cefadroxil (CDX), a new semisynthetic cephalosporin derivative, was administered to 20 patients with acute or chronic otolaryngological infections and following results were obtained. Of 11 cases with acute infections such as acute otitis media, acute otitis externa and postoperative maxillary cyst, excellent, good and fair results were obtained in 10 cases, the efficacy ratio being 91%, while the efficacy ratio in 9 cases with chronic infections such as chronic pharyngolaryngitis and chronic otitis media was 56%. CDX is, therefore, extremely effective for acute otolaryngological infections. No severe side effect was observed, although there were 2 cases with minor adverse effects, one with drug induced eruption and the other with stomatitis.
头孢羟氨苄(CDX)是一种新型半合成头孢菌素衍生物,对20例急慢性耳鼻喉科感染患者进行了治疗,并取得了以下结果。在11例急性感染患者中,如急性中耳炎、急性外耳道炎和上颌囊肿术后,10例获得了优、良和中等效果,有效率为91%,而在9例慢性感染患者中,如慢性咽喉炎症和慢性中耳炎,有效率为56%。因此,CDX对急性耳鼻喉科感染极为有效。未观察到严重副作用,尽管有2例出现轻微不良反应,1例出现药物性皮疹,另1例出现口腔炎。