[The intraglobular electrostatic field of an enzyme. II. Effect of environment polarization].

The influence of polarization of surrounding medium on the intraglobular electric field of the alpha-chymotrypsin molecule is considered. The polarization is taken into account by the image charges method, the proper approximations for calculation of the fields due to intraglobular and surface charges are suggested. The polarization of surroundings does not change the qualitative picture of the electric field in the active center of the alpha-chymotrypsin molecule set up by protein dipoles, but reduces almost to zero the intraglobular field set up by surface ions.