镉对海洋生物的致死和亚致死效应——关于“安全水平”的批判性讨论

Lethal and sublethal effects of cadmium on marine organisms--a critical discussion about "safety levels".

作者信息

Sperling K R

出版信息

Ecotoxicol Environ Saf. 1983 Dec;7(6):521-4. doi: 10.1016/0147-6513(83)90009-x.

PMID:6662052

Abstract

The applicability of terms such as "safety level" and "safety factor" for the purpose of risk assessment in the frame of the marine dumping conventions is discussed. In view of a series of experiments on sublethal effects of cadmium on marine organisms it is stated that the dose-response relationships cover a range of 10(4), and that there is no indication that the lowest level found so far is actually just above a no-effect threshold.

摘要

讨论了“安全水平”和“安全系数”等术语在海洋倾倒公约框架内用于风险评估的适用性。鉴于一系列关于镉对海洋生物亚致死效应的实验，指出剂量反应关系涵盖了10的4次方范围，并且没有迹象表明迄今发现的最低水平实际上仅略高于无效应阈值。