Göretzlehner G
Z Gesamte Inn Med. 1983 Nov 15;38(22):251-3.
The wide-spread usual habits of contraception plead for the fact that hormonal contraceptives after a longer time, possibly till beyond the change of the millennium, will be applied as the most secure remedy of prevention of pregnancy. The author deals with the hormonal contraceptives being at the disposal in the GDR, such as combination preparations, sequential preparations week pill, minipill, postcoital contraception. It is referred to the fact that the variety of hormonal contraceptives being at our disposal is fully to be used and the prescription has to be done corresponding to the hormone-depending symptoms on the basis of the anamnesis. Mode of intake, reliability, control measures, the pro and contra of an interval in taking the pill, the prescription to young girls as well as the subdivision of the side-effects on account of their clinical importance are treated. The criteria which lead to the assessment of innocuousness and tolerability are also to be taken into consideration as the evidence got by casuistics, controlled clinical studies and epidemiological studies and its possible misinterpretations. The argument takes place on the basis of the mortality risks for cardiovascular diseases. The necessary consequences are pointed out: establishment of the mortality risks on the basis of GDR-owned cohort- and trohoc-studies, differentiation of the findings not only according to the hormonal contraceptives in general, but preparation-specific, increase of the autoresponsibility of the user.
广泛使用的避孕习惯表明,在较长时间内,可能直到千禧年之后,激素避孕药将作为预防怀孕的最安全方法被应用。作者探讨了民主德国可供使用的激素避孕药,如复方制剂、序贯制剂、周效口服避孕药、迷你避孕药、性交后避孕。文中提到,我们可使用的各种激素避孕药都应充分利用,并且必须根据问诊得出的激素相关症状进行处方。文中还讨论了服药方式、可靠性、控制措施、服药间隔的利弊、给年轻女孩的处方以及根据副作用的临床重要性对其进行的分类。导致对无害性和耐受性进行评估的标准也应予以考虑,以及个案法、对照临床研究和流行病学研究获得的证据及其可能的误解。讨论基于心血管疾病的死亡风险展开。文中指出了必要的后果:根据民主德国的队列研究和病例对照研究确定死亡风险,不仅要根据一般的激素避孕药,还要根据具体制剂对研究结果进行区分,提高使用者的自我责任意识。