[Cutaneous resorption of actellic (O,2-diethylamino-6-methyl pyrimidin-4-yl-O,O-dimethyl phosphorothioate) in the presence of high temperature and humidity].

Studies were carried out on the combined effect of high relative humidity and temperature on stability and dynamics of skin actelic resorption. Actelic resorption with skin application was established to be uneven. The initial resorption of the substance by the skin, was followed by its increased concentration on skin surface, and a further decrease and maintenance with a general tendency to decrease of the concentration. Humidity accelerated resorption, whereas with the combination of high temperature and high relative humidity--an reverse tendency was observed.