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[Alpha 1-acid glycoprotein and carbamazepine].

作者信息

Bruguerolle B, Bussière H, Jadot G

出版信息

Rev Neurol (Paris). 1983;139(11):679-80.

PMID:6677980
Abstract

Levels of alpha 1-acid glycoprotein (alpha 1-AGP) were determined in 40 epileptic patients who had been also treated with carbamazepine (CBZ) and, in some patients, phenobarbital (PB) for at least 3 months. alpha 1-AGP levels were also determined in 28 controls. CBZ dit not alter blood levels of alpha 1-AGP while CBZ-PB decreased them. Such results are at variance with recent studies which suggested an increase of alpha 1-AGP in epileptic patients treated either with phenytoin or phenytoin + PB, or + CBZ, or + primidone.

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