咖啡因与持续气道扩张压在新生儿呼吸暂停中的相互作用
Interaction of caffeine and continuous distending airway pressure in neonatal apnea.
作者信息
Aranda J V, Outerbridge E W, Trippenbach T
出版信息
Am J Perinatol. 1983 Oct;1(1):43-6. doi: 10.1055/s-2007-1000051.
PMID:6680651
Abstract
The interactive effect of caffeine and continuous distending airway pressure was evaluated in two premature neonates with apnea. The application of a continuous negative pressure around the chest wall decreased minute ventilation in both infants and blunted the stimulatory effect of caffeine. This potential interaction should be considered if the desired effects of caffeine or distending airway pressure on apnea control are not achieved when they are used concurrently.
摘要
在两名患有呼吸暂停的早产新生儿中评估了咖啡因与持续气道扩张压力的交互作用。在两名婴儿的胸壁周围施加持续负压均降低了分钟通气量，并减弱了咖啡因的刺激作用。如果同时使用咖啡因或气道扩张压力时未达到对呼吸暂停控制的预期效果，则应考虑这种潜在的相互作用。
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