在腺苷酸脱氨酶缺乏的情况下，运动肌肉不会产生次黄嘌呤。
Exercising muscle does not produce hypoxanthine in adenylate deaminase deficiency.
作者信息
Patterson V H, Kaiser K K, Brooke M H
出版信息
Neurology. 1983 Jun;33(6):784-6. doi: 10.1212/wnl.33.6.784.
PMID:6682523
Abstract
The failure of forearm exercise to increase plasma hypoxanthine in subjects with adenylate deaminase deficiency confirms this enzyme's role in hypoxanthine production by normal forearm exercise. The conversion of adenosine monophosphate (AMP) to hypoxanthine may reflect an alternative method of adenosine triphosphate (ATP) regeneration in working muscle.
摘要
在腺苷酸脱氨酶缺乏的受试者中，前臂运动未能增加血浆次黄嘌呤，这证实了该酶在正常前臂运动产生次黄嘌呤过程中的作用。一磷酸腺苷（AMP）转化为次黄嘌呤可能反映了工作肌肉中三磷酸腺苷（ATP）再生的另一种方式。
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