Tykkä H, Oravisto K J, Lehtonen T, Sarna S, Tallberg T
Eur Urol. 1978;4(4):250-8. doi: 10.1159/000473966.
The results of a specific active immunotherapy method following palliative nephrectomy in 31 patients suffering from advanced renal-cell carcinoma are presented. The control patient group comprised of 23 comparable cases, who did not receive immunotherapy. The minimum follow-up time for any patient is 4 years. The statistical 5-year survival rate of the immunotherapy group is 23.6% (SE = 7.8). 7 patients are still alive. The 5-year survival rate of the control group is 4.3% (SE = 4.3), without a single survival. The difference is statistically highly significant (p less than 0.001). No side effects were noted from this form of immunotherapy.
本文展示了31例晚期肾细胞癌患者在姑息性肾切除术后采用特定主动免疫疗法的结果。对照组由23例未接受免疫疗法的可比病例组成。所有患者的最短随访时间为4年。免疫疗法组的统计学5年生存率为23.6%(标准误=7.8)。7例患者仍存活。对照组的5年生存率为4.3%(标准误=4.3),无一例存活。差异具有高度统计学意义(p<0.001)。这种免疫疗法未观察到副作用。