Suppr超能文献

[急性自愿性卡比咪嗪中毒伴室性心动过速]

[Acute voluntary carpipramine poisoning with ventricular tachycardia].

作者信息

Racle J P, Maman G, Beligon C, Curabet D

出版信息

Ann Fr Anesth Reanim. 1984;3(1):52-3. doi: 10.1016/s0750-7658(84)80100-8.

Abstract

A case of carpipramine overdose is reported. The patient was admitted with ventricular tachycardia 4 h after taking 2.40 g of the drug. This disappeared at the sixth hour. In overdoses with other tricyclics, ventricular tachycardia was successfully treated within 30 min of starting a sodium lactate perfusion. In the case presented, reversal of the ventricular tachycardia coincided with the half-life of the drug; the effects of perfusing 1000 ml sodium lactate over 2 h seemed doubtful. This sodium resistance may be related to a relative hypokalemia (3.4 mmol X 1(-1) ). The use of sodium lactate for the treatment of overdoses with drugs with short-half lives appeared questionable.

摘要

报告了一例卡比咪嗪过量病例。患者在服用2.40克该药物4小时后因室性心动过速入院。这种情况在第六小时消失。在其他三环类药物过量时,在开始乳酸钠灌注30分钟内室性心动过速得到成功治疗。在本病例中,室性心动过速的逆转与药物的半衰期一致;在2小时内灌注1000毫升乳酸钠的效果似乎存疑。这种对钠的抵抗可能与相对低钾血症(3.4毫摩尔×1(-1))有关。使用乳酸钠治疗半衰期短的药物过量情况似乎存在问题。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验