Rhodes R H
Graefes Arch Clin Exp Ophthalmol. 1984;221(4):171-8. doi: 10.1007/BF02134260.
The posterior retina of human embryos from 4 to 200 mm of crown-rump length was studied by electron microscopy. At 20 mm dense inner Müller-cell processes near ganglion cells contained rough endoplasmic reticulum, free ribosomes, small matrix particles, and some intermediate filaments. These processes soon had smooth endoplasmic reticulum. By 71 mm many of these inner processes were lucent and contained many intermediate filaments and glycogen particles. Müller-cell nuclei and outer processes were observed between differentiating cone cells at 66 mm, and these outer radial-cell processes soon contained many dense matrix particles and glycogen particles. As neurons in the inner nuclear layer differentiated by 100 mm, Müller-cell cytoplasm in the mid-retina was identified by its intermediate filaments and glycogen particles. Müller cells have composite glial features that appear in the horizontal retinal layers concomitant with neuronal differentiation and maturation in each layer.
通过电子显微镜研究了冠臀长4至200毫米的人类胚胎的视网膜后部。在20毫米时，神经节细胞附近密集的内米勒细胞突起含有粗面内质网、游离核糖体、小基质颗粒和一些中间丝。这些突起很快就有了滑面内质网。到71毫米时，许多这些内部突起变得透明，含有许多中间丝和糖原颗粒。在66毫米时，在分化的视锥细胞之间观察到米勒细胞核和外部突起，这些外部放射状细胞突起很快就含有许多致密的基质颗粒和糖原颗粒。随着内核层中的神经元在100毫米时分化，视网膜中部的米勒细胞胞质通过其中间丝和糖原颗粒得以识别。米勒细胞具有复合性神经胶质特征，这些特征出现在视网膜水平层中，与各层神经元的分化和成熟同时发生。
