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[雷诺病中的血液流变学]

[Blood rheology in Raynaud's disease].

作者信息

Larcan A, Schmidt C, Stoltz J F, Voisin P

出版信息

J Mal Vasc. 1984;9(1):1-6.

PMID:6707529
Abstract

The part played by blood rheological factors in any vasomotor phenomenon is still difficult to define, in relation to its onset, maintenance and possible worsening. A high viscosity may contribute towards a difficulty in flow and viscosity is known to vary in an inverse manner with temperature. Many studies have been published reporting results of rheological investigations in Raynaud's syndromes, but whereas the majority describe both blood and plasma hyperviscosity, others report negative results or those that are interpretable with difficulty. A recent study in 49 patients with Raynaud's syndromes confirmed the presence of elevated blood and plasma viscosity values, particularly in Raynaud's syndromes secondary to other disorders and in digital arteritis. Elevated viscosity levels in "essential" Raynaud's syndromes were significant at low speeds only, suggesting the association of a disorder of erythrocyte aggregation with the properly termed vasomotor disturbance.

摘要

血液流变学因素在任何血管舒缩现象中所起的作用,就其发生、维持及可能的恶化而言,仍难以界定。高粘度可能导致血流困难,而且已知粘度与温度呈反比变化。已经发表了许多关于雷诺综合征血液流变学研究结果的报告,但大多数报告描述了血液和血浆的高粘度,其他报告则得出阴性结果或难以解释的结果。最近一项对49例雷诺综合征患者的研究证实了血液和血浆粘度值升高,特别是在继发于其他疾病的雷诺综合征和指动脉炎中。“原发性”雷诺综合征中升高的粘度水平仅在低速时显著,提示红细胞聚集紊乱与确切的血管舒缩障碍有关。

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