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[胰岛素依赖型糖尿病患者的生长激素和催乳素水平]

[Somatotropin and prolactin levels in patients with insulin-dependent diabetes mellitus].

作者信息

Golikova A A

出版信息

Probl Endokrinol (Mosk). 1984 Jan-Feb;30(1):8-11.

PMID:6709609
Abstract

Radioimmunoassay was used to measure the content of somatotropic hormone and prolactin in the blood of patients with insulin-dependent diabetes in relation to the duration and degree of diabetic complications in a state of decompensation and during compensation. To have a more descriptive idea of the interrelation between prolactin and somatotrophic hormone (STH), the prolactin/STH index was introduced (the ratio of prolactin indicators to those of STH). Altogether 66 patients aged from 16 to 50 years were examined. A direct relationship was disclosed between an increase in the STH content and the degree of diabetic complications. The prolactin level was found to be elevated only in content was recorded in patients with a more long-term disease. During compensation, the patients with insulin-depended diabetes manifested a reduction in the STH level and an increase in the prolactin/STH index.

摘要

采用放射免疫分析法测定胰岛素依赖型糖尿病患者在失代偿期和代偿期血液中生长激素和催乳素的含量,以研究其与糖尿病并发症的病程和严重程度之间的关系。为了更全面地描述催乳素与生长激素(STH)之间的相互关系,引入了催乳素/STH指数(催乳素指标与STH指标的比值)。共检查了66例年龄在16至50岁之间的患者。发现STH含量的增加与糖尿病并发症的严重程度之间存在直接关系。仅在病程较长的患者中记录到催乳素水平升高。在代偿期,胰岛素依赖型糖尿病患者的STH水平降低,催乳素/STH指数升高。

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