Kokot F, Grzeszczak W, Duława J
Z Gesamte Inn Med. 1984 Feb 1;39(3):40-3.
In 14 healthy persons, 31 patients with acute and 13 with chronic renal failure the influence of alpha-bromocriptine on the PTH and prolactin level in the blood serum was investigated. In all subjects examined alpha-bromocriptine caused a decrease of the prolactin level. In acute and chronic renal failure simultaneously a decrease, on the other hand in healthy persons an increase of the PTH-concentration was observed. In all groups examined no correlation between the PTH and the prolactin level could be stated. In the light of the results obtained in this study the existence of a direct PTH-depending prolactin secretion seems to be questionable.
在14名健康人、31名急性肾衰竭患者和13名慢性肾衰竭患者中,研究了α-溴隐亭对血清中甲状旁腺激素(PTH)和催乳素水平的影响。在所有接受检查的受试者中,α-溴隐亭均导致催乳素水平下降。另一方面,在急性和慢性肾衰竭患者中观察到PTH浓度下降,而在健康人中则观察到PTH浓度升高。在所有检查的组中,均未发现PTH与催乳素水平之间存在相关性。根据本研究获得的结果,PTH直接依赖的催乳素分泌的存在似乎值得怀疑。