Schwandner G K, Betzler M, Götze V
Chirurg. 1984 Mar;55(3):168-70.
The therapy of choice in cases with the prognostically poor (mean 5-year-survival rate maximal 12%) and rare anorectal melanoma is the surgical removal. Primary local excision should be done if technically feasible. On the basis of an exact pathohistological examination with special respect to tumor thickness a radical exstirpation or resection should be performed in cases with lesions more than 2 mm thick. In patients with tumors less than 2 mm a clinically and endoscopically follow-up in short intervals (3 months) after local excision can be recommended. At present, no effective radiotherapy nor systemic treatment exist.
对于预后较差(平均5年生存率最高为12%)且罕见的肛管直肠黑色素瘤病例,首选治疗方法是手术切除。若技术可行,应进行原发灶局部切除。在进行精确的病理组织学检查并特别关注肿瘤厚度的基础上,对于肿瘤厚度超过2mm的病例,应进行根治性切除。对于肿瘤小于2mm的患者,局部切除后可建议短期内(3个月)进行临床和内镜随访。目前,尚无有效的放疗或全身治疗方法。