Davison T F, Rea J
Gen Comp Endocrinol. 1984 Jan;53(1):86-9. doi: 10.1016/0016-6480(84)90227-2.
Accumulation of radioiodide by the thyroids of individual domestic fowl was measured with the technique described by T. F. Davison, J. G. Rowell, and J. Rea, [1981) J. Endocrinol. 89, 371-378). Radioiodide uptake was markedly decreased in birds given an excess of iodide in the drinking water (60 mg KI/liter) or injections of thyroxine (T4: 5 X 50 micrograms T4/kg body wt), in agreement with published findings. Treatment with a goitrogen (250 mg methimazole/liter drinking water) decreased 125I uptake for at least 8 days but thereafter uptake increased and this was accompanied by gross thyroidal enlargement. The results indicate that the thyroid partly compensates for goitrogenic inhibition.
采用T. F. 戴维森、J. G. 罗威尔和J. 雷[1981年，《内分泌学杂志》89卷，371 - 378页]所描述的技术，对个体家禽甲状腺对放射性碘化物的蓄积情况进行了测量。与已发表的研究结果一致，给家禽饮用过量碘化物（60毫克碘化钾/升）或注射甲状腺素（T4：5×50微克T4/千克体重）后，放射性碘摄取量显著降低。用致甲状腺肿物质（250毫克甲巯咪唑/升饮用水）处理至少8天可降低125I摄取量，但此后摄取量增加，同时伴有甲状腺明显肿大。结果表明，甲状腺可部分代偿致甲状腺肿物质的抑制作用。
