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静息状态下定量平衡放射性核素心室造影在评估冠心病严重程度中的应用

[Quantitative equilibrium radionuclide ventriculography at rest in the evaluation of the severity of coronary disease].

作者信息

Knesewitsch P, Kleinhans E, Seiderer M, Doliwa R, Büll U

出版信息

Nuklearmedizin. 1984 Feb;23(1):41-6.

PMID:6728693
Abstract

The results of examining 373 patients with a quantitative equilibrium radionuclide ventriculography were stored in a data bank and evaluated statistically. The following left ventricular parameters were evaluated: global and regional ejection fractions ( gEF , rEF1 - rEF5 ) and volume parameters (EDV, ESV, stroke volume, cardiac output, heart index). It appeared that in stages I and II of coronary heart disease evaluation of gEF , EDV and ESV under resting conditions does not sufficiently discriminate diseased patients from normals. Significant changes (p less than 0.025) of these parameters (vs. normal) were found only in CHD III and IV or in patients with a history of old myocardial infarction. The additional evaluation of the regional fraction yields, however, a significant increase (CHD I and II: +25%) of the sensitivity of the equilibrium radionuclide ventriculography in the diagnosis of coronary heart disease.

摘要

对373例患者进行定量平衡放射性核素心室造影检查的结果存储在数据库中,并进行统计学评估。评估了以下左心室参数:整体和局部射血分数(gEF、rEF1 - rEF5)以及容积参数(EDV、ESV、每搏输出量、心输出量、心脏指数)。结果显示,在冠心病的I期和II期,静息状态下gEF、EDV和ESV的评估不足以将患病患者与正常患者区分开来。仅在冠心病III期和IV期或有陈旧性心肌梗死病史的患者中发现这些参数(与正常相比)有显著变化(p小于0.025)。然而,对局部分数的额外评估使平衡放射性核素心室造影在冠心病诊断中的敏感性显著提高(冠心病I期和II期:提高25%)。

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