Abbott A, Hayes M L
J Gen Microbiol. 1984 Apr;130(4):809-16. doi: 10.1099/00221287-130-4-809.
The solution properties of saliva and its role in conditioning both the substrate and the bacterial surface have been investigated with regard to the attachment of oral streptococci to hydroxyapatite surfaces. Saliva from eight subjects was used and the attachment of three organisms, Streptococcus mutans strains FA-1 (serotype b) and KPSK2 (serotype c) and S. sanguis T175-1, was studied. An adsorbed salivary layer on a hydroxyapatite surface substantially reduced the affinity of the organisms for the surface. Adsorbed saliva on the bacterial surfaces, however, tended to increase the organisms' affinity for saliva-coated apatite. The source of saliva was important in determining the extent of inhibition of attachment. The data indicated that the negatively charged and hydrophilic nature of salivary conditioning films was important in controlling bacterial adsorption to hydroxyapatite. The results also suggested that hydrophobic salivas could promote binding of the more hydrophobic bacteria known to be early colonizers of the teeth.
关于口腔链球菌在羟基磷灰石表面的附着，研究了唾液的溶液性质及其在调节底物和细菌表面方面的作用。使用了来自八名受试者的唾液，并研究了三种微生物——变形链球菌FA-1菌株（血清型b）、KPSK2菌株（血清型c）和血链球菌T175-1——的附着情况。羟基磷灰石表面上吸附的唾液层大大降低了微生物对该表面的亲和力。然而，细菌表面吸附的唾液往往会增加微生物对唾液包被的磷灰石的亲和力。唾液来源在决定附着抑制程度方面很重要。数据表明，唾液调节膜的负电荷和亲水性在控制细菌对羟基磷灰石的吸附中很重要。结果还表明，疏水性唾液可以促进已知为牙齿早期定植菌的更疏水细菌的结合。
