Farrell K, Chuang S, Becker L E
Ann Neurol. 1984 Jun;15(6):605-7. doi: 10.1002/ana.410150616.
Computed tomography demonstrated contrast-enhancing lesions in the periventricular frontal regions, caudate nuclei, and thalami in an infant with Alexander's disease. The distribution of the enhancing lesions corresponded to the areas in which Rosenthal fibers were most prominent. These radiological findings have not been described in other white matter diseases; thus, they may help to distinguish Alexander's disease from Canavan's disease and decrease the necessity for diagnostic brain biopsy.
计算机断层扫描显示，一名患有亚历山大病的婴儿在脑室周围额叶区域、尾状核和丘脑出现了强化病变。强化病变的分布与罗森塔尔纤维最突出的区域相对应。这些影像学表现尚未在其他白质疾病中描述过；因此，它们可能有助于将亚历山大病与卡纳万病区分开来，并减少诊断性脑活检的必要性。
