MacLean A B
Br J Obstet Gynaecol. 1984 Jul;91(7):697-706. doi: 10.1111/j.1471-0528.1984.tb04834.x.
The recognition that only a minority of cervical premalignant lesions progress to invasion, and the increasing incidence of these lesions in young women, has led to a more conservative approach in the treatment of cervical intraepithelial neoplasia. One such method uses the carbon dioxide laser but inadequate length of follow-up has prevented a prediction of risk of recurrence. Observations made in this study on the speed of healing, source of new epithelium, maturation of the epithelium and the absence of herpes nucleic acid suggest that this risk is low.
认识到只有少数宫颈癌前病变会发展为浸润性癌,且这些病变在年轻女性中的发病率不断上升,这使得在宫颈上皮内瘤变的治疗上采取了更为保守的方法。其中一种方法是使用二氧化碳激光,但随访时间不足阻碍了对复发风险的预测。本研究中关于愈合速度、新上皮来源、上皮成熟情况以及疱疹核酸缺失的观察表明,这种风险较低。