De Roo M, Devos P, Goffin J, van den Bergh R
Eur J Nucl Med. 1982;7(8):345-52. doi: 10.1007/BF00255652.
A method for multiparametric quantitative cerebral angioscintigraphy is described. For the evaluation of the symmetry of hemispherical bolus transit the following parameters were used: the cumulative L/R hemispheric ratios expressed in arctangent values and the sequential hemispheric activity difference. Both the sensitivity and specificity of this technique for detection of proven stenosis of carotid or cerebral arteries (25 cases) were 80%, in comparison with 60% for computerized axial tomography. A few clinical examples illustrate the diagnostic utility of quantitative cerebral angioscintigraphy. The value of the different quantitative parameters is discussed and compared with other similar studies. With regard to the complementary role of computerized axial tomography and serial cerebral scintigraphy the results of other authors were confirmed. Considering the broad field of application for dynamic brain scintigraphy and the fact that both sensitivity and specificity of this exploration are comparable to, or even better than, CT, it is our opinion that isotopic exploration remains a reliable detection method for cerebrovascular disease.
本文描述了一种多参数定量脑血池闪烁造影术。为评估半球团注通过的对称性，使用了以下参数：以反正切值表示的累积左/右半球比率和连续半球活性差异。与计算机断层扫描60%的灵敏度和特异度相比，该技术检测已证实的颈动脉或脑动脉狭窄（25例）的灵敏度和特异度均为80%。一些临床实例说明了定量脑血池闪烁造影术的诊断效用。讨论了不同定量参数的价值，并与其他类似研究进行了比较。关于计算机断层扫描和系列脑闪烁造影的互补作用，证实了其他作者的结果。考虑到动态脑闪烁造影术的广泛应用领域，以及该检查的灵敏度和特异度与CT相当甚至更好这一事实，我们认为同位素检查仍然是一种可靠的脑血管疾病检测方法。
