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恒河猴(猕猴)和豚尾猴(猪尾猕猴)中的促黄体生成激素释放激素通路:关于厚的、未包埋切片的新观察结果

The luteinizing hormone-releasing hormone pathways in rhesus (Macaca mulatta) and pigtailed (Macaca nemestrina) monkeys: new observations on thick, unembedded sections.

作者信息

Silverman A J, Antunes J L, Abrams G M, Nilaver G, Thau R, Robinson J A, Ferin M, Krey L C

出版信息

J Comp Neurol. 1982 Nov 1;211(3):309-17. doi: 10.1002/cne.902110309.

DOI:10.1002/cne.902110309
PMID:6757282
Abstract

Immunocytochemical procedures on thick, unembedded tissue sections were used to study the localization of LHRH neurons and fibers in the diencephalon and mesencephalon of rhesus and pigtailed macaques. Cell bodies were visualized in large numbers. Much of their dendritic arborization was also filled with reaction product. Cell bodies were present in the preoptic area, the periventricular hypothalamic zone from the level of the anterior hypothalamus to the premammillary nuclei, the infundibular nucleus, supraoptic nucleus, several septal nuclei, the nervus terminalis, and the amygdala. The localization of LHRH cells in several of these areas represents new observations. LHRH axons were observed to innervate the portal vessels in the median eminence, the organum vasculosum of the lamina terminalis, the median eminence, the organum vasculosum of the lamina terminalis, the medial mammillary nuclei, the epithalamus, and the amygdala. These observations are discussed in relationship to the regulation of gonadotropin secretion in the primate.

摘要

采用对未包埋的厚组织切片进行免疫细胞化学方法,研究恒河猴和豚尾猕猴间脑和中脑促性腺激素释放激素(LHRH)神经元及纤维的定位。大量细胞体清晰可见。它们的大部分树突分支也充满了反应产物。细胞体存在于视前区、从前下丘脑水平到乳头前核的室周下丘脑区、漏斗核、视上核、几个隔核、终纹床核和杏仁核。LHRH细胞在其中几个区域的定位代表了新的观察结果。观察到LHRH轴突支配正中隆起的门脉血管、终板血管器、正中隆起、终板血管器、内侧乳头核、上丘脑和杏仁核。结合灵长类动物促性腺激素分泌的调节对这些观察结果进行了讨论。

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