Zeman R K, Taylor K J, Rosenfield A T, Schwartz A, Gold J A
AJR Am J Roentgenol. 1981 May;136(5):965-7. doi: 10.2214/ajr.136.5.965.
Three dogs were serially studied with sonography after cholecystectomy and total acute biliary obstruction. Peripheral biliary dilatation could be diagnosed as early as 4 hr after biliary obstruction and before significant elevation of serum bilirubin. These experimental results support the thesis that total biliary obstruction may be diagnosed before the onset of icterus.