Hawkins T D, Occleshaw J V
Clin Radiol. 1978 Jul;29(4):463-7. doi: 10.1016/s0009-9260(78)80112-3.
Total body opacification in infants following the intravenous injection of a large dose of water soluble contrast medium has long been recognised, but no example of increased radiodensity of abdominal or intracranial tumours has been reported using this technique. This paper reports the sustained opacification of intracranial tumours in three infants during cerebral angiography. Two of the tumours were papillomas of the choroid plexus of the lateral ventricle and the third a medulloblastoma of the fourth ventricle. Three possible explanations of this phenomenon are briefly considered: 1. That the amount of contrast medium was sufficient to cause total body opacification and the visibility of the tumours was due to a combination of their vascularity and the iodine concentration in the circulation blood. 2. That the observed phenomenon is peculiar to these tumours. 3. That the sustained opacity of these these tumours is due to the same cause or causes as the density enhancement of some intracranial tumours demonstrated by computerised tomography after intravenous injection of contrast medium.
大剂量水溶性造影剂静脉注射后婴儿全身显影早已为人所知，但尚未有使用该技术使腹部或颅内肿瘤放射密度增加的报道。本文报告了3例婴儿在脑血管造影期间颅内肿瘤持续显影的情况。其中2例肿瘤为侧脑室脉络丛乳头状瘤，第3例为第四脑室髓母细胞瘤。本文简要考虑了这种现象的三种可能解释：1. 造影剂的量足以导致全身显影，肿瘤的显影是由于其血管分布和循环血液中碘浓度共同作用的结果。2. 观察到的这种现象是这些肿瘤所特有的。3. 这些肿瘤持续显影的原因与静脉注射造影剂后计算机断层扫描显示的一些颅内肿瘤密度增强的原因相同。
