Bueno M, Pérez-González J, Sarria A
An Esp Pediatr. 1981 Jul;15(1):13-22.
Association of histocompatibility antigen (HLA antigens) with collagen diseases is not a casual event. Even known data, the practical conclusions have a limited usefullness because there is not a definitive correspondence between HLA antigens and rheumatic diseases. With HLA typing is possible to determine risk populations. The pauciarticular type II of juvenile reumatoid arthritis (J.R.A) is associated with HLA-B27 in the 75% of cases. Also, this antigen is associated with ankylosing spondylitis, Reiter's disease, Behçet disease, psoriasic arthritis, reactive arthritis (yersinia, shigella, salmonella). Systemic lupus erythematosus has been described associated with HLA-B8 and HLA-DRw2.
