针对D抗原致敏个体的淋巴细胞对O、Rh阳性（R1R2）红细胞的直接抗体依赖细胞介导的细胞毒性裂解作用。
Direct ADCC lysis of O,Rh-positive (R1R2) erythrocytes by lymphocytes of individuals sensitized against antigen D.
作者信息
Bakács T, Ringwald G, Jókuti I
出版信息
Immunol Lett. 1982 Jan;4(1):53-7. doi: 10.1016/0165-2478(82)90078-5.
PMID:6800939
Abstract
Non-T-cells from individuals sensitized against antigen D were found to lyze O,Rh-positive erythrocytes. The lytic effect was abolished by incubation of the effector cells at 37 degrees C for 30 min, and was reconstituted by addition of anti-D antibodies. These results suggested that sensitized donors have lymphocytes armed with specific antibodies in vivo.
摘要
发现对抗原D致敏个体的非T细胞能溶解O型、Rh阳性红细胞。效应细胞在37℃孵育30分钟后，其溶解作用消失，加入抗D抗体后又恢复。这些结果表明，致敏供体体内有携带特异性抗体的淋巴细胞。
Zotero 插件