Rognoni J B, Simon C
C R Seances Acad Sci III. 1982 Jan 4;294(1):25-30.
Rats were submitted to an iodine deficient diet during 6 months. At the end of this treatment, normal iodine diet was given to the animals during 16 days. For the first two days of iodine refeeding, thyroidal iodide was strongly stored, which is explained by a very stimulated iodide pump and by an iodination blockade. After this latency, the thyroidal iodide promptly decreased whereas iodide pump was always activated, and iodination still inhibited. A retroinhibition by thyroidal iodide on its active transport is postulated.
大鼠接受了6个月的缺碘饮食。在该治疗结束时，给动物喂食正常碘饮食16天。在碘再喂养的前两天，甲状腺碘化物大量储存，这可由非常活跃的碘泵和碘化阻断来解释。在这个潜伏期之后，甲状腺碘化物迅速减少，而碘泵始终处于激活状态，碘化仍受抑制。推测甲状腺碘化物对其主动转运存在逆向抑制作用。
