Saxena R, Kumar S, Tandon S N, Jain P C
Indian J Physiol Pharmacol. 1978 Jan-Mar;22(1):39-43.
In dogs anaesthetised with pentobarbitone sodium, raising the body temperature from 37 degrees C to 42 degrees C increased the rate of respiration and pulmonary ventilation but decreased the tidal volume. A similar change though of a lower magnitude, was observed in these parameters after cold blocking the vagi. At 40 degrees C body temperature, however, the vagal block was not effective in reducing the rate. The significance of hyperthermic panting mechanism dominating the Hering-Breuer mechanism at 40 degrees C has been discussed. It has been postulated that the vagi carry temperature dependent afferents that have effect opposite to the Hering-Breuer reflex. At 42 degrees C when respiratory failure usually sets in the temperature regulating function of respiration is the last to be lost.
在戊巴比妥钠麻醉的犬中，将体温从37℃升至42℃会增加呼吸频率和肺通气量，但会降低潮气量。在迷走神经冷阻断后，这些参数也观察到了类似但程度较低的变化。然而，在体温为40℃时，迷走神经阻断对降低呼吸频率无效。已经讨论了在40℃时高温喘息机制主导黑林-布雷尔机制的意义。据推测，迷走神经携带与温度相关的传入神经，其作用与黑林-布雷尔反射相反。在42℃时，当呼吸衰竭通常开始时，呼吸的体温调节功能是最后丧失的。
