Muldoon R L, Raucci J, Kowalski J, Rajashekaraiah K
Ann Emerg Med. 1982 Nov;11(11):613-5. doi: 10.1016/s0196-0644(82)80203-5.
Of approximately 200 members of a religious commune, 37 came to the emergency department of Cook County Hospital for primary medical care of respiratory illness. Of the 37, 31 were seen during a two-week period, indicating a rapid spread of disease. The major symptoms were cough, fever, coryza, and sore throat. Infiltrates were detected in 38%. Paired sera from four of nine patients showed a significant rise to Mycoplasma pneumoniae. Of 24 sera collected at the time of the first visit, 33% had a titer to the agent, of 64 or greater--presumptive evidence of Mycoplasma infection. Therefore, M pneumoniae was implicated as the causative agent in this outbreak of respiratory illness in a semi-closed community.
在一个宗教公社的约200名成员中,有37人前往库克县医院急诊科接受呼吸道疾病的初级医疗护理。在这37人中,有31人在两周内前来就诊,表明疾病传播迅速。主要症状为咳嗽、发热、鼻塞和喉咙痛。38%的患者检测到肺部浸润。9名患者中的4名配对血清显示对肺炎支原体有显著升高。在首次就诊时采集的24份血清中,33%对该病原体的滴度达到64或更高——这是肺炎支原体感染的推定证据。因此,肺炎支原体被认为是这个半封闭社区此次呼吸道疾病暴发的病原体。