男性双侧睾丸切除术后的垂体-甲状腺轴
Pituitary-thyroid axis after bilateral orchiectomy in men.
作者信息
Valenti G, Banchini A, Zavaroni D, Vescovi P P, Ponticelli P, Hafez E S
出版信息
Arch Androl. 1982 Sep;9(2):171-4. doi: 10.3109/01485018208990236.
The functional interaction between the testis and thyroid was evaluated in 13 patients affected by prostatic carcinoma before and after bilateral orchiectomy. Two different patterns of thyroid hormones were noted. Immediately after surgery, free thyroxine (T4) increased and total triiodothyronine (T3) decreased probably as a result of surgical stress at anesthesia. Later, free T4 levels decreased while total T4 and thyroxine binding globulin (TBG) were unchanged. Such changes may be due to qualitative changes in binding proteins.
在13例前列腺癌患者双侧睾丸切除术前和术后，对睾丸与甲状腺之间的功能相互作用进行了评估。观察到两种不同的甲状腺激素模式。术后即刻，游离甲状腺素（T4）升高，总三碘甲状腺原氨酸（T3）降低，这可能是麻醉手术应激的结果。随后，游离T4水平下降，而总T4和甲状腺素结合球蛋白（TBG）未发生变化。这些变化可能是由于结合蛋白的质性改变所致。
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