Horst R L, Jorgensen N A
J Dairy Sci. 1982 Dec;65(12):2332-7. doi: 10.3168/jds.S0022-0302(82)82505-8.
The relationship of cortisol in blood plasma with plasma calcium and phosphorus was studied from 3 days before to 2.5 days after calving in 12 dairy cows (third or more parity). Cows were in three groups: 1) paretic (displayed hypocalcemic and lateral recumbency), 2) nonparetic (plasma calcium at least 8.0 mg/100 ml), and 3) borderline (plasma calcium less than 8.0 mg/100 ml). Cortisol concentrations from 0 to 1.5 days postpartum reflected the state of calcium stress of the groups, paretic more than borderline and borderline more than nonparetic. Phosphorus was lower from 0 to 1 day postpartum in paretic cows. Calcium and phosphorus were negatively correlated (within cow) with cortisol (-.53, -.37). In experiments with goats, cortisol was released in response to hypocalcemia and displayed no activity in initiating an onset of hypocalcemia when given exogenously. Also, the observation that cortisol-treated goats responded less severely with calcium depression and recovered faster from induced hypocalcemia by ethylene glycol-bis (beta-amino-ethyl ester) N,N'-tetraacetic acid infusions suggests cortisol may aid the animal in recovering from hypocalcemia.
对12头经产（第三胎及以上）奶牛产犊前3天至产后2.5天血浆皮质醇与血浆钙和磷的关系进行了研究。奶牛分为三组：1）瘫痪组（出现低钙血症并侧卧），2）非瘫痪组（血浆钙至少8.0mg/100ml），3）临界组（血浆钙低于8.0mg/100ml）。产后0至1.5天的皮质醇浓度反映了各组的钙应激状态，瘫痪组高于临界组，临界组高于非瘫痪组。瘫痪奶牛产后0至1天的磷含量较低。钙和磷（在同一头牛体内）与皮质醇呈负相关（分别为-.53和-.37）。在山羊实验中，皮质醇因低钙血症而释放，外源性给予时在引发低钙血症发作方面无活性。此外，观察到经皮质醇处理的山羊对钙降低的反应较轻，并且通过输注乙二醇双（β-氨基乙酯）N,N'-四乙酸诱导低钙血症后恢复更快，这表明皮质醇可能有助于动物从低钙血症中恢复。
