Tabei T, Tsukui T, Nomoto C, Suemasu K, Higashi Y
Jpn J Clin Oncol. 1983 Mar;13(1):61-6.
A case of juvenile thyroid carcinoma with metastasis to the bilateral cervical lymph nodes in a 9-year-old male is reported. The clinical picture of juvenile thyroid carcinoma is characterized by early metastasis to the lungs and cervical lymph nodes. In Europe, there have been many reports of thyroid carcinoma after radiation. However, our patient had received no radiation. Surgery consisted of subtotal thyroidectomy and right modified neck dissection. The tumor was a papillary adenocarcinoma and metastasis was seen in 24 out of 38 lymph nodes removed. The serum thyroglobulin level, determined by radioimmunoassay, was 184 ng/ml preoperatively, but by 8 months postoperatively the level fell to 48 ng/ml. No signs of recurrence have been found to date (30 months after the operation).
报告了一例9岁男性青少年甲状腺癌伴双侧颈部淋巴结转移的病例。青少年甲状腺癌的临床表现特点是早期转移至肺部和颈部淋巴结。在欧洲,有许多关于放疗后甲状腺癌的报道。然而,我们的患者未接受过放疗。手术包括甲状腺次全切除术和右侧改良颈清扫术。肿瘤为乳头状腺癌,在切除的38个淋巴结中有24个发现转移。术前通过放射免疫测定法测定的血清甲状腺球蛋白水平为184 ng/ml,但术后8个月该水平降至48 ng/ml。迄今为止(手术后30个月)未发现复发迹象。