Bilkey W J, Awad E A, Smith A D
J Urol. 1983 Jun;129(6):1187-9. doi: 10.1016/s0022-5347(17)52632-4.
We determined the sacral reflex latency in 108 neurologically normal subjects and 110 patients with neurological lesions by applying stimulating current to the glans penis or clitoris and measuring the response with electrodes inserted in the external urethral and anal sphincters. In normal men the mean latencies were 34.6 plus or minus 5.1 (standard deviation) msec. at the external urethral sphincter and 36.0 plus or minus 5.2 msec. at the external anal sphincter. In normal women the mean latencies were 37.4 plus or minus 5.5 msec. at the external urethral sphincter and 38.6 plus or minus 4.0 msec. at the external anal sphincter. The mean reflex latency in patients with upper motor neuron lesions was significantly shorter. To our knowledge this is the first single electrophysiological test to show a difference between such patients and normal subjects. An increased mean latency was found in patients with lower motor neuron impairment. We conclude that measurement of sacral reflex latency can add to the diagnostic information obtained from conventional electromyography and cystometry.
我们通过向阴茎头或阴蒂施加刺激电流，并将电极插入尿道外括约肌和肛门外括约肌来测量反应，从而测定了108名神经功能正常的受试者和110名有神经病变患者的骶反射潜伏期。在正常男性中，尿道外括约肌的平均潜伏期为34.6±5.1（标准差）毫秒，肛门外括约肌的平均潜伏期为36.0±5.2毫秒。在正常女性中，尿道外括约肌的平均潜伏期为37.4±5.5毫秒，肛门外括约肌的平均潜伏期为38.6±4.0毫秒。上运动神经元病变患者的平均反射潜伏期明显较短。据我们所知，这是首个显示此类患者与正常受试者之间存在差异的单一电生理测试。下运动神经元损伤患者的平均潜伏期增加。我们得出结论，骶反射潜伏期的测量可以增加从传统肌电图和膀胱测压获得的诊断信息。
