Ishchenko M M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(7):1026-34.
A clinical study of 70 patients with cerebral rheumovasculitis permitted the author to distinguish 3 forms of the disease: with a diffuse, mild focal and crude focal neorological symptomatology. Their dependence upon the somatical signs is demonstrated, a successional development of nervous system lesions, treatment and its effectiveness. The histochemical studies in different brain areas in patients with crude focal neorological symptomatology demonstrated allergic, metabolic and inflammatory changes in the vascular walls, accompanied by hemodynamical changes and deep dystrophy of the neurons and nervous fibres, as well as productive reaction of the astrocytes, oligodendrocytes and microglial elements.
对70例脑风湿性血管炎患者的临床研究使作者能够区分出该疾病的3种形式：具有弥漫性、轻度局灶性和重度局灶性神经症状。阐述了它们与躯体体征的相关性、神经系统病变的连续发展、治疗方法及其有效性。对具有重度局灶性神经症状的患者不同脑区进行的组织化学研究表明，血管壁存在过敏、代谢和炎症变化，伴有血流动力学变化以及神经元和神经纤维的深度营养不良，同时星形胶质细胞、少突胶质细胞和小胶质细胞成分有增生反应。
