Winkelmann E, Oelssner W, Morgenstern R, Brauer K, Hedlich A, Werner L, Senitz D
J Hirnforsch. 1983;24(1):1-7.
Neurons of the Wistar-rats' occipital cortex were morphologically investigated after chronical application of amphetamine. The nerve cells impregnated according to the Golgi-Kopsch technique showed in part changes on both the dendrites and in the axonal region. Besides a partial reduction of spines and of peripheral dendritic arborizations round varicosities of different density could be observed on the dendrites and on the axon, either, which were discussed to be due to a neurotoxic effect of amphetamine.
在长期使用苯丙胺后,对Wistar大鼠枕叶皮质的神经元进行了形态学研究。根据高尔基-科普希技术浸染的神经细胞在树突和轴突区域均出现了部分变化。除了树突棘部分减少外,在树突和轴突上还可观察到不同密度的曲张周围的外周树突分支减少,这被认为是苯丙胺神经毒性作用所致。