阿普林定肝炎

Aprindine hepatitis.

作者信息

Herlong H F, Reid P R, Boitnott J K, Maddrey W C

出版信息

Ann Intern Med. 1978 Sep;89(3):359-61. doi: 10.7326/0003-4819-89-3-359.

Abstract

We have seen two patients whose hepatitis was due to the administration of aprindine, a new antiarrhythmic agent. In both patients evidence of hepatitis appeared within 3 weeks of initiating aprindine therapy and resolved rapidly when the drug was withdrawn. The reintroduction of aprindine in one patient was associated with the reappearance of hepatitis, which resolved despite continued administration of the drug.

摘要

我们见过两名患者，他们的肝炎是由一种新型抗心律失常药物安搏律定的使用引起的。在这两名患者中，肝炎迹象均在开始使用安搏律定治疗的3周内出现，停药后迅速消退。在其中一名患者中，重新使用安搏律定与肝炎再次出现有关，尽管继续用药，但肝炎仍消退了。