Chatterjee M, Murphy R A
Science. 1983 Jul 29;221(4609):464-6. doi: 10.1126/science.6867722.
Stress development depended on calcium-stimulated myosin phosphorylation in an arterial smooth muscle preparation in which the concentration of calcium was controlled. However, developed stress was maintained at a concentration of calcium that did not support phosphorylation. These results, in conjunction with other evidence, suggest that the interaction of two regulatory mechanisms with different calcium sensitivities regulate both stress and the rate and energetics of contraction.
在一种可控制钙浓度的动脉平滑肌制剂中，张力的产生依赖于钙刺激的肌球蛋白磷酸化。然而，在不支持磷酸化的钙浓度下，已产生的张力仍能维持。这些结果与其他证据一起表明，两种具有不同钙敏感性的调节机制相互作用，共同调节张力以及收缩的速率和能量消耗。
