Franz E, Bosse K, Beck B
Arch Dermatol Res. 1978 Jul 28;262(2):167-72. doi: 10.1007/BF00455386.
In the "clean" rat skin purified from the panniculus carnosus the oxygen consumption of the spontaneous and artificially induced skincycle was measured at different times of day. The level of oxygen consumption correlated to diurnal and nocturnal periods. During the skincycle the oxygen consumption showed fluctuations. There were indications that the value of oxygen consumption of the early anagen is influenced by that phase of the cycle at which the new cycle is artificially induced. Furthermore, it was found that a certain decrease of oxygen consumption stimulates the quiescent hair follicles to spontaneous proliferation. During the katagen the peak value of the oxygen consumption seemed to be correlated with specially morphofunctional perifollicular changes. The application of these findings to the pathophysiology of human hair growth disturbances is discussed.
在从肉膜中纯化得到的“清洁”大鼠皮肤中,测定了一天中不同时间自发和人工诱导的皮肤周期的耗氧量。耗氧量水平与昼夜周期相关。在皮肤周期中,耗氧量呈现波动。有迹象表明,早期生长期的耗氧量值受人工诱导新周期时所处周期阶段的影响。此外,还发现耗氧量的一定降低会刺激静止毛囊自发增殖。在退行期,耗氧量的峰值似乎与毛囊周围特殊的形态功能变化相关。讨论了这些发现应用于人类毛发生长紊乱病理生理学的情况。