肝细胞、库普弗细胞和内皮细胞的膜脂
Membrane lipids of hepatocytes, Kupffer cells and endothelial cells.
作者信息
Gabellec M M, Steffan A M, Dodeur M, Durand G, Kirn A, Rebel G
出版信息
Biochem Biophys Res Commun. 1983 Jun 29;113(3):845-53. doi: 10.1016/0006-291x(83)91076-8.
PMID:6870894
Abstract
The membrane lipid composition of isolated hepatocytes, Kupffer cells and endothelial cells was determined. The hepatocytes are characterized by a lower quantity of gangliosides, cholesterol, sphingomyelin and a reduced cholesterol/phospholipid molar ratio when compared to the two other liver cell types. The main gangliosides of Kupffer and endothelial cells are the GM3 species, and those of hepatocytes are of the polysialogangliosides species.
摘要
测定了分离的肝细胞、库普弗细胞和内皮细胞的膜脂质组成。与其他两种肝细胞类型相比，肝细胞的神经节苷脂、胆固醇、鞘磷脂含量较低，胆固醇/磷脂摩尔比降低。库普弗细胞和内皮细胞的主要神经节苷脂是GM3种类，而肝细胞的主要神经节苷脂是多唾液酸神经节苷脂种类。
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