High-performance liquid chromatographic determination of reproterol in plasma using on-line trace enrichment and amperometric detection with a rotating working electrode.

A method is described to determine nanogram quantities of reproterol in plasma. It consists of deproteinization of the plasma samples, on-line trace enrichment, and liquid chromatographic separation of the compounds brought on the analytical column, coupled with amperometric detection. Reliable quantitation can be done down to levels of 1 ng/ml.