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乳膏分析。V. 薄层色谱法的应用。第二部分。

Analysis of creams. V. Application of thin layer chromatography. Part II.

作者信息

Van de Vaart F J, Hulshoff A, Indemans A W

出版信息

Pharm Weekbl Sci. 1983 Jun 24;5(3):113-8. doi: 10.1007/BF01960987.

Abstract

A standard TLC procedure was tested for its applicability in the qualitative analysis of several creams. It was found that in creams of known composition the presence of almost all of the active cream components as well as the excipients can be confirmed. An additional eluent, spray reagent, or a liquid extraction clean-up step sometimes appeared to be necessary. If the cream base composition is not known, a 'fingerprint' of the various types of excipients is obtained with the described procedure.

摘要

对一种标准的薄层色谱法(TLC)在几种乳膏定性分析中的适用性进行了测试。结果发现,在已知成分的乳膏中,几乎所有活性乳膏成分以及辅料的存在都可以得到确认。有时似乎需要额外的洗脱剂、喷雾试剂或液液萃取净化步骤。如果乳膏基质成分未知,则可通过所述程序获得各类辅料的“指纹图谱”。

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