Discrete nonlinear reduction model for horizontal cell response in the carp retina.

In this paper we present a new model for the spatial behavior of the external horizontal cells in the carp retina which elucidates more precisely the mechanisms of their intercellular connections. The area and intensity effects of a brief light stimulus on the L-type response were recorded and analysed. We discovered clear nonlinearities in the behavior of the response which could not be explained by the simple summative model presently accepted. Proposed here is a new model, the spatial reduction mechanism, which explains the experimental evidences including these nonlinearities. We also present the results of a computer simulation using our new model in parallel with the actual results obtained experimentally. The physiological implications of these findings are discussed.