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浆肌层空肠补片在感染性主动脉残端保护中的临床应用。

Clinical use of the seromuscular jejunal patch for protection of the infected aortic stump.

作者信息

Shah D M, Buchbinder D, Leather R P, Corson J, Karmody A M

出版信息

Am J Surg. 1983 Aug;146(2):198-202. doi: 10.1016/0002-9610(83)90372-0.

Abstract

Pathologic interactions between aortic prostheses and the gastrointestinal tract are very difficult problems in vascular surgery. After excision of the graft and proximal aortic closure, the major unsolved problem has been continued sepsis of the proximal aortic stump with subsequent fatal disruption. To provide healthy tissue for protection of this crucial area, we have devised a method in which a piece of jejunum on its vascular pedicle is opened along its antimesenteric border, the mucosa is removed, and the vascularized muscular wall is anchored to the aortic stump. This seromuscular jejunal patch was used clinically in three patients. Postmortem examinations in two of these patients 4 and 45 days postoperatively revealed no signs of infection, hematoma, or mucocele, and no histologic abnormalities; instead, the examinations did reveal firm tissue adherence between the aortic stumps and the seromuscular patches. The third patient is alive and well 1 year after this procedure. The three patients have demonstrated the feasibility of secure aortic stump protection by placement of well-prepared, vascularized seromuscular jejunal tissue over the potentially infected aortic stump. This technique may prevent postoperative stump dissolution and thus far appears to be a reasonable solution to this usually lethal problem.

摘要

主动脉假体与胃肠道之间的病理相互作用是血管外科中非常棘手的问题。在切除移植物并进行近端主动脉闭合后,主要的未解决问题一直是近端主动脉残端持续发生败血症,随后导致致命的破裂。为了提供健康组织来保护这个关键区域,我们设计了一种方法,即沿其血管蒂将一段空肠沿其系膜对侧缘打开,去除黏膜,然后将带血管的肌壁固定在主动脉残端。这种浆肌层空肠补片已在3例患者中临床应用。其中2例患者在术后4天和45天进行的尸检未发现感染、血肿或黏液囊肿迹象,也未发现组织学异常;相反,检查确实显示主动脉残端与浆肌层补片之间有牢固的组织粘连。第三名患者在该手术后1年存活且状况良好。这3例患者证明了通过在潜在感染的主动脉残端上放置精心准备的带血管浆肌层空肠组织来安全保护主动脉残端的可行性。这项技术可能会防止术后残端溶解,并且迄今为止似乎是解决这个通常致命问题的合理方法。

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